An extensive body of research documents and supports the principles of osteopathy, the effectiveness of osteopathic manipulation, and the physiologic components of the primary respiratory mechanism (PRM).

Resources here include:

  • A bibliography of the most often cited and most useful research on osteopathic manipulation
  • An analytic discussion of the current state of research on the efficacy and physiologic components of cranial osteopathy
  • Research news  that is interesting or pertinent to practicing osteopaths, especially from the allopathic and translational science literature.  You can also “like” the Osteopathic Cranial Academy  Facebook page to get this research news on your Facebook news feed.

Two new papers published in Science in November 2019 shows fluctuation of the CSF during deep sleep at approximately 20 seconds per cycle;  you can see the video here.  This was described by the research team in process reports as “the movement appears almost tidal.”  Modern science is catching up with Dr. Sutherland.


Note that much of the supporting research has been published in the Journal of the American Osteopathic Association (JAOA), which may not be included in all medical databases and so is missed by many researchers in doing literature searches.   Searching the JAOA directly will enhance the results of most literature searches.